On October 16, 1846, dentist William T.G. Morton administered inhaled diethyl ether to patient Gilbert Abbott at Massachusetts General Hospital in Boston. Surgeon John Collins Warren then removed a vascular tumor from Abbott's neck while the patient reported no pain. Morton had tested ether on a tooth extraction two weeks earlier. The demonstration established inhaled anesthesia as a viable surgical tool, though priority remains disputed — Crawford Long had used ether in surgery in 1842, and Morton spent his remaining years in legal conflicts over the claim.